Regulatory Network in Protein Phosphorylation
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Substrate: OCLN

Description: Occludin.

Ensembl ID: ENSG00000197822

UniprotKB/SwissProt: OCLN_HUMAN (Q16625)

Function: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Multi-pass membrane protein. Cell junction, tight junction.
PDB:1WPA
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of OCLN

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1OCLNOCLN_HUMANT305NVSAG T QDVPS 22.70% Swiss-Prot 55.0 View   
2OCLNOCLN_HUMANS340RFYPE S SYKST 34.17%PKCg HPRD:04191(in vitro)  ViewAnalyzing
3OCLNOCLN_HUMANS340RFYPE S SYKST 34.17%PKCa HPRD:04191(in vitro)  ViewAnalyzing
4OCLNOCLN_HUMANS340RFYPE S SYKST 34.17%PKC_group Phospho.ELM 7.0 ViewAnalyzing
5OCLNOCLN_HUMANS340RFYPE S SYKST 34.17%PKCb HPRD:04191(in vitro)  ViewAnalyzing
6OCLNOCLN_HUMANT404ETDYT T GGESC 36.64%P67870(Casein kinase II, beta) HPRD:04191(in vitro) ViewAnalyzing
7OCLNOCLN_HUMANT404ETDYT T GGESC 36.64%CK2_group Phospho.ELM 7.0 ViewAnalyzing
8OCLNOCLN_HUMANS408TTGGE S CDELE 30.09%P67870(Casein kinase II, beta) HPRD:04191(in vitro) ViewAnalyzing
9OCLNOCLN_HUMANS408TTGGE S CDELE 30.09%CK2_group Phospho.ELM 7.0 ViewAnalyzing