Regulatory Network in Protein Phosphorylation
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Substrate: PPP1R1B

Description: Protein phosphatase 1 regulatory subunit 1B (Dopamine- and cAMP-regulated neuronal phosphoprotein) (DARPP-32).

Synonyms: DARPP32

Ensembl ID: ENSG00000131771

UniprotKB/SwissProt: PPR1B_HUMAN (Q9UD71)

Function: Inhibitor of protein-phosphatase 1.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PPP1R1B

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PPP1R1BPPR1B_HUMANT34RRRRP T PAMLF 23.13%PKACa HPRD:05097(in vitro)  ViewAnalyzing
2PPP1R1BPPR1B_HUMANT34RRRRP T PAMLF 23.13%PKA_group Swiss-Prot 55.0 (Similarity) ViewAnalyzing
3PPP1R1BPPR1B_HUMANS45RLSEH S SPEEE 43.46%CK2a1-rs HPRD:05097(in vitro)  ViewAnalyzing
4PPP1R1BPPR1B_HUMANS45RLSEH S SPEEE 43.46%CK2a1 HPRD:05097(in vitro)  ViewAnalyzing
5PPP1R1BPPR1B_HUMANS45RLSEH S SPEEE 43.46%CK2a2 HPRD:05097(in vitro)  ViewAnalyzing
6PPP1R1BPPR1B_HUMANS66GHHLK S KRPNP 40.01%CK2a1 HPRD:05097(in vitro)  ViewAnalyzing
7PPP1R1BPPR1B_HUMANS66GHHLK S KRPNP 40.01%CK2a2 HPRD:05097(in vitro)  ViewAnalyzing
8PPP1R1BPPR1B_HUMANS66GHHLK S KRPNP 40.01%CK2a1-rs HPRD:05097(in vitro)  ViewAnalyzing
9PPP1R1BPPR1B_HUMANT75NPCAY T PPSLK 15.36%CDK5 Swiss-Prot 55.0   ViewAnalyzing
10PPP1R1BPPR1B_HUMANT75NPCAY T PPSLK 15.36%CDK5 HPRD:05097(in vitro;in vivo)  ViewAnalyzing
11PPP1R1BPPR1B_HUMANT75NPCAY T PPSLK 15.36%CDK_group Phospho.ELM 7.0 ViewAnalyzing
12PPP1R1BPPR1B_HUMANS102NENQA S EEEDE 35.46%CK2a1-rs HPRD:05097(in vitro)  ViewAnalyzing
13PPP1R1BPPR1B_HUMANS102NENQA S EEEDE 35.46%CK2a2 HPRD:05097(in vitro)  ViewAnalyzing
14PPP1R1BPPR1B_HUMANS102NENQA S EEEDE 35.46%CK2a1 HPRD:05097(in vitro)  ViewAnalyzing
15PPP1R1BPPR1B_HUMANS198EPQRP S PSEPG 43.16% Swiss-Prot 55.0 (Similarity)View