Regulatory Network in Protein Phosphorylation
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Substrate: RANGAP1

Description: Ran GTPase-activating protein 1 (RanGAP1).

Synonyms: SD

UniprotKB/SwissProt: RAGP1_HUMAN (P46060)

Function: GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity).
PDB:1Z5S
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of RANGAP1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1RANGAP1RAGP1_HUMANS358VLASL S DDEDE 40.29%CK2a1 HPRD:03839(in vitro)  ViewAnalyzing
2RANGAP1RAGP1_HUMANS358VLASL S DDEDE 40.29%CK2a1-rs HPRD:03839(in vitro)  ViewAnalyzing
3RANGAP1RAGP1_HUMANS428APVLS S PPPAD 36.95% Swiss-Prot 55.0 View   
4RANGAP1RAGP1_HUMANS428APVLS S PPPAD 36.95% HPRD:03839(in vivo)View   
5RANGAP1RAGP1_HUMANS428APVLS S PPPAD 36.95% Phospho.ELM 7.0View   
6RANGAP1RAGP1_HUMANT436PADVS T FLAFP 23.63% Phospho.ELM 7.0View   
7RANGAP1RAGP1_HUMANT436PADVS T FLAFP 23.63% HPRD:03839(in vivo)View   
8RANGAP1RAGP1_HUMANS442FLAFP S PEKLL 38.96% Phospho.ELM 7.0View   
9RANGAP1RAGP1_HUMANS442FLAFP S PEKLL 38.96% HPRD:03839(in vivo)View   
10RANGAP1RAGP1_HUMANS442FLAFP S PEKLL 38.96% Swiss-Prot 55.0 View