Regulatory Network in Protein Phosphorylation
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Substrate: RGS1

Description: Regulator of G-protein signaling 1 (RGS1) (Early response protein1R20) (B-cell activation protein BL34).

Synonyms: 1R20, BL34, IER1

Ensembl ID: ENSG00000090104

UniprotKB/SwissProt: RGS1_HUMAN (Q08116)

Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
PDB:2BV1
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of RGS1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1RGS1RGS1_HUMANS19KGTTH S LLDDK 28.65%CK2_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
2RGS1RGS1_HUMANS54ESGMK S SKSKD 33.82%PKC_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
3RGS1RGS1_HUMANS62SKDVL S AAEVM 25.86%CK2_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
4RGS1RGS1_HUMANT146RTRES T AKKIK 37.43%PKC_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
5RGS1RGS1_HUMANT156KAPTP T CFDEA 28.43%CK2_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
6RGS1RGS1_HUMANT167QKVIY T LMEKD 14.43%CK2_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
7RGS1RGS1_HUMANS194DLQAN S LK 40.32%PKC_group Swiss-Prot 55.0 (Potential) ViewAnalyzing