Regulatory Network in Protein Phosphorylation
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Substrate: SP1

Description: Transcription factor Sp1.

Synonyms: TSFP1

Ensembl ID: ENSG00000185591

UniprotKB/SwissProt: SP1_HUMAN (P08047)

Function: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of SP1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1SP1SP1_HUMANS7SDQDH S MDEMT 35.90% Swiss-Prot 55.0 (Similarity)View   
2SP1SP1_HUMANS59QESQP S PLALL 25.55% Swiss-Prot 55.0 View   
3SP1SP1_HUMANS59QESQP S PLALL 25.55% Phospho.ELM 7.0View   
4SP1SP1_HUMANS59QESQP S PLALL 25.55% HPRD:01796(in vivo)View   
5SP1SP1_HUMANT453PIIIR T PTVGP 16.95%Erk1 HPRD:01796(in vitro;in vivo)  ViewAnalyzing
6SP1SP1_HUMANT453PIIIR T PTVGP 16.95%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
7SP1SP1_HUMANT453PIIIR T PTVGP 16.95%Erk2 HPRD:01796(in vitro;in vivo)  ViewAnalyzing
8SP1SP1_HUMANT453PIIIR T PTVGP 16.95%Erk2(MAPK1) Phospho.ELM 7.0 ViewAnalyzing
9SP1SP1_HUMANT579GIHDD T AGGEE 33.01%CK2a1-rs HPRD:01796(in vitro)  ViewAnalyzing
10SP1SP1_HUMANT579GIHDD T AGGEE 33.01%CK2_group Phospho.ELM 7.0 ViewAnalyzing
11SP1SP1_HUMANT579GIHDD T AGGEE 33.01%CK2a1 HPRD:01796(in vitro)  ViewAnalyzing
12SP1SP1_HUMANT739GSGTA T PSALI 20.02%Erk2 HPRD:01796(in vitro;in vivo)  ViewAnalyzing
13SP1SP1_HUMANT739GSGTA T PSALI 20.02%Erk2(MAPK1) Phospho.ELM 7.0 ViewAnalyzing
14SP1SP1_HUMANT739GSGTA T PSALI 20.02%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
15SP1SP1_HUMANT739GSGTA T PSALI 20.02%Erk1 HPRD:01796(in vitro;in vivo)  ViewAnalyzing