|Description: Osteopontin precursor (Bone sialoprotein 1) (Secreted phosphoprotein1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).|
Synonyms: BNSP, OPN
Ensembl ID: ENSG00000118785
UniprotKB/SwissProt: OSTP_HUMAN (P10451)
Function: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted.