|Description: Activated RNA polymerase II transcriptional coactivator p15 (SUB1homolog) (Positive cofactor 4) (PC4) (p14).|
Synonyms: PC4, RPO2TC1
Ensembl ID: ENSG00000113387
UniprotKB/SwissProt: TCP4_HUMAN (P53999)
Function: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.