Regulatory Network in Protein Phosphorylation
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Substrate: SUB1

Description: Activated RNA polymerase II transcriptional coactivator p15 (SUB1homolog) (Positive cofactor 4) (PC4) (p14).

Synonyms: PC4, RPO2TC1

Ensembl ID: ENSG00000113387

UniprotKB/SwissProt: TCP4_HUMAN (P53999)

Function: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
PDB:1PCF
Protein Domain and Phosphorylation Sites: