|Description: Transducin-like enhancer protein 2 (ESG2).|
Ensembl ID: ENSG00000065717
UniprotKB/SwissProt: TLE2_HUMAN (Q04725)
Function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.