|Description: Vesicle-associated membrane protein 4 (VAMP-4).|
Ensembl ID: ENSG00000117533
UniprotKB/SwissProt: VAMP4_HUMAN (O75379)
Function: Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein (Probable). Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.