|Description: Serine/threonine-protein kinase TAO3 (EC 22.214.171.124) (Thousand and oneamino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Dendritic cell-derived protein kinase) (CutaneousT-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09)(Kinase from chicken homolog A) (hKFC-A).|
Synonyms: DPK, JIK, KDS, MAP3K18
Ensembl ID: ENSG00000135090
UniprotKB/SwissProt: TAOK3_HUMAN (Q9H2K8)
Function: Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also localized to the peripheral cell membrane.