Regulatory Network in Protein Phosphorylation
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Substrate: ELK1

Description: ETS domain-containing protein Elk-1.

Ensembl ID: ENSG00000126767

UniprotKB/SwissProt: ELK1_HUMAN (P19419)

Function: Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
PDB:1DUX
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ELK1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ELK1ELK1_HUMANS324LELPL S PSLLG 15.54%Erk2(MAPK1) Swiss-Prot 55.0  ViewAnalyzing
2ELK1ELK1_HUMANT336PGPER T PGSGS 30.27%Erk2(MAPK1) Swiss-Prot 55.0  ViewAnalyzing
3ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
4ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%p38a HPRD:02407(in vitro)  ViewAnalyzing
5ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%JNK2 HPRD:02407(in vitro)  ViewAnalyzing
6ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%JNK2(MAPK9) Phospho.ELM 7.0 ViewAnalyzing
7ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%TAO2 HPRD:02407(in vitro)  ViewAnalyzing
8ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%Erk2 HPRD:02407(in vitro)  ViewAnalyzing
9ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%Erk2(MAPK1) Swiss-Prot 55.0  ViewAnalyzing
10ELK1ELK1_HUMANS383FWSTL S PIAPR 17.85%p38a(MAPK14) Phospho.ELM 7.0 ViewAnalyzing
11ELK1ELK1_HUMANS389PIAPR S PAKLS 28.31%p38a HPRD:02407(in vitro)  ViewAnalyzing
12ELK1ELK1_HUMANS389PIAPR S PAKLS 28.31%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
13ELK1ELK1_HUMANS389PIAPR S PAKLS 28.31%JNK2 HPRD:02407(in vitro)  ViewAnalyzing
14ELK1ELK1_HUMANS389PIAPR S PAKLS 28.31%JNK2(MAPK9) Phospho.ELM 7.0 ViewAnalyzing
15ELK1ELK1_HUMANS389PIAPR S PAKLS 28.31%Erk2(MAPK1) Swiss-Prot 55.0  ViewAnalyzing
16ELK1ELK1_HUMANS389PIAPR S PAKLS 28.31%p38a(MAPK14) Phospho.ELM 7.0 ViewAnalyzing
17ELK1ELK1_HUMANT417VDGLS T PVVLS 25.74%PRP4 Phospho.ELM 7.0  ViewAnalyzing
18ELK1ELK1_HUMANS422TPVVL S PGPQK 19.05%Erk2(MAPK1) Swiss-Prot 55.0  ViewAnalyzing