Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinase ABL2(ARG)]
Substrate: ANXA1

Description: Annexin A1 (Annexin-1) (Annexin I) (Lipocortin I) (Calpactin II)(Chromobindin-9) (p35) (Phospholipase A2 inhibitory protein).

Synonyms: ANX1, LPC1

Ensembl ID: ENSG00000135046

UniprotKB/SwissProt: ANXA1_HUMAN (P04083)

Function: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, cilium (By similarity). Basolateral cell membrane (By similarity). Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By simi
PDB:1AIN
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ANXA1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ANXA1ANXA1_HUMANS5-MAMV S EFLKQ 15.00%ChaK1(TRPM7) Swiss-Prot 55.0  ViewAnalyzing
2ANXA1ANXA1_HUMANS5-MAMV S EFLKQ 15.00% Phospho.ELM 7.0View   
3ANXA1ANXA1_HUMANS5-MAMV S EFLKQ 15.00%ChaK1 HPRD:01060(in vitro;in vivo)  ViewAnalyzing
4ANXA1ANXA1_HUMANY21NEEQE Y VQTVK 9.50%SRC HPRD:01060(in vitro)  ViewAnalyzing
5ANXA1ANXA1_HUMANY21NEEQE Y VQTVK 9.50%Src Phospho.ELM 7.0  ViewAnalyzing
6ANXA1ANXA1_HUMANY21NEEQE Y VQTVK 9.50%EGFR Phospho.ELM 7.0  ViewAnalyzing
7ANXA1ANXA1_HUMANY21NEEQE Y VQTVK 9.50%ABL1 Phospho.ELM 7.0  ViewAnalyzing
8ANXA1ANXA1_HUMANY21NEEQE Y VQTVK 9.50%EGFR Swiss-Prot 55.0   ViewAnalyzing
9ANXA1ANXA1_HUMANT24QEYVQ T VKSSK 21.62%PKC_group Phospho.ELM 7.0 ViewAnalyzing
10ANXA1ANXA1_HUMANT24QEYVQ T VKSSK 21.62% Swiss-Prot 55.0 View   
11ANXA1ANXA1_HUMANS27VQTVK S SKGGP 32.71%PKC_group Swiss-Prot 55.0  ViewAnalyzing
12ANXA1ANXA1_HUMANS27VQTVK S SKGGP 32.71%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
13ANXA1ANXA1_HUMANS27VQTVK S SKGGP 32.71%PKC_group Phospho.ELM 7.0 ViewAnalyzing
14ANXA1ANXA1_HUMANS27VQTVK S SKGGP 32.71%PKCi HPRD:01060(in vitro)  ViewAnalyzing
15ANXA1ANXA1_HUMANS28QTVKS S KGGPG 29.60%PKC_group Phospho.ELM 7.0 ViewAnalyzing
16ANXA1ANXA1_HUMANY207DARAL Y EAGER 11.62% Swiss-Prot 55.0 View   
17ANXA1ANXA1_HUMANT216ERRKG T DVNVF 39.55%PKA_group Phospho.ELM 7.0 ViewAnalyzing
18ANXA1ANXA1_HUMANT216ERRKG T DVNVF 39.55% HPRD:01060(in vitro)View