|Description: Breakpoint cluster region protein (EC 220.127.116.11) (Renal carcinomaantigen NY-REN-26).|
Synonyms: BCR1, D22S11
Ensembl ID: ENSG00000186716
UniprotKB/SwissProt: BCR_HUMAN (P11274)
Function: GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: