|Description: Tyrosine-protein kinase BTK (EC 18.104.22.168) (Bruton tyrosine kinase)(Agammaglobulinaemia tyrosine kinase) (ATK) (B-cell progenitor kinase)(BPK).|
Synonyms: AGMX1, ATK, BPK
Ensembl ID: ENSG00000010671
UniprotKB/SwissProt: BTK_HUMAN (Q06187)
Function: Plays a crucial role in B-cell ontogeny. Transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Required for the formation of functional ARID3A DNA-binding complexes.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity). Nucleus (By similarity).