Regulatory Network in Protein Phosphorylation
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Substrate: CD19

Description: B-lymphocyte antigen CD19 precursor (Differentiation antigen CD19) (B-lymphocyte surface antigen B4) (Leu-12).

Ensembl ID: ENSG00000177455

UniprotKB/SwissProt: CD19_HUMAN (P15391)

Function: Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CD19

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CD19CD19_HUMANS227PKSLL S LELKD 25.70% Swiss-Prot 55.0 (Similarity)View   
2CD19CD19_HUMANY348GPQNQ Y GNVLS 20.44%Erk2 HPRD:00113(in vitro)  ViewAnalyzing
3CD19CD19_HUMANY348GPQNQ Y GNVLS 20.44% Phospho.ELM 7.0View   
4CD19CD19_HUMANY348GPQNQ Y GNVLS 20.44% Swiss-Prot 55.0 View   
5CD19CD19_HUMANY378GTAPS Y GNPSS 21.62% Swiss-Prot 55.0 View   
6CD19CD19_HUMANY378GTAPS Y GNPSS 21.62%Erk2 HPRD:00113(in vitro)  ViewAnalyzing
7CD19CD19_HUMANY378GTAPS Y GNPSS 21.62% Phospho.ELM 7.0View   
8CD19CD19_HUMANY409EEGEG Y EEPDS 16.90% Phospho.ELM 7.0View   
9CD19CD19_HUMANY409EEGEG Y EEPDS 16.90%LYN HPRD:00113(in vitro)  ViewAnalyzing
10CD19CD19_HUMANY409EEGEG Y EEPDS 16.90%Erk2 HPRD:00113(in vitro)  ViewAnalyzing
11CD19CD19_HUMANY409EEGEG Y EEPDS 16.90% Swiss-Prot 55.0 View   
12CD19CD19_HUMANY439QDGSG Y ENPED 17.77% Swiss-Prot 55.0 View   
13CD19CD19_HUMANY439QDGSG Y ENPED 17.77%Erk2 HPRD:00113(in vitro)  ViewAnalyzing
14CD19CD19_HUMANY439QDGSG Y ENPED 17.77% Phospho.ELM 7.0View   
15CD19CD19_HUMANS497ATSLG S QSYED 22.65% Swiss-Prot 55.0 View   
16CD19CD19_HUMANY500LGSQS Y EDMRG 14.33%Lyn Phospho.ELM 7.0  ViewAnalyzing
17CD19CD19_HUMANY500LGSQS Y EDMRG 14.33%BTK HPRD:00113(in vitro)  ViewAnalyzing
18CD19CD19_HUMANY500LGSQS Y EDMRG 14.33%LYN HPRD:00113(in vitro;in vivo)  ViewAnalyzing
19CD19CD19_HUMANY508MRGIL Y AAPQL 9.97%ABL1 HPRD:00113(in vitro;in vivo)  ViewAnalyzing
20CD19CD19_HUMANY531EDADS Y ENMDN 16.33%Lyn Phospho.ELM 7.0  ViewAnalyzing
21CD19CD19_HUMANY531EDADS Y ENMDN 16.33%BTK HPRD:00113(in vitro)  ViewAnalyzing
22CD19CD19_HUMANY531EDADS Y ENMDN 16.33%LYN HPRD:00113(in vitro;in vivo)  ViewAnalyzing