|Description: Cell division protein kinase 5 (EC 220.127.116.11) (Cyclin-dependent kinase5) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)(Serine/threonine-protein kinase PSSALRE).|
Ensembl ID: ENSG00000164885
UniprotKB/SwissProt: CDK5_HUMAN (Q00535)
Function: Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Cell projection, lamellipodium (By similarity). Cell projection, growth cone (By similarity). Note=In axonal growth cone with extension to the peripheral lamellipodia (By similarity).