|Description: Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependentphospholipid scramblase 4) (TRA1) (Cell growth-inhibiting gene 43protein).|
Ensembl ID: ENSG00000114698
UniprotKB/SwissProt: PLS4_HUMAN (Q9NRQ2)
Function: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane; Single-pass type II membrane protein (By similarity).