Regulatory Network in Protein Phosphorylation
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Substrate: RAD51

Description: DNA repair protein RAD51 homolog 1 (hRAD51) (HsRAD51).

Synonyms: RAD51A, RECA

Ensembl ID: ENSG00000051180

UniprotKB/SwissProt: RAD51_HUMAN (Q06609)

Function: May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Note=Colocalizes with RAD51AP1 to multiple nuclear foci upon induction of DNA damage.
PDB:1B22
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of RAD51

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1RAD51RAD51_HUMANY54VEAVA Y APKKE 19.48%ABL1 HPRD:01557(in vitro)  ViewAnalyzing
2RAD51RAD51_HUMANY54VEAVA Y APKKE 19.48%ABL1 Phospho.ELM 7.0  ViewAnalyzing
3RAD51RAD51_HUMANT309KGRGE T RICKI 28.32%CHK1 Swiss-Prot 55.0   ViewAnalyzing
4RAD51RAD51_HUMANT309KGRGE T RICKI 28.32% Phospho.ELM 7.0View   
5RAD51RAD51_HUMANY315RICKI Y DSPCL 8.89%ABL1 HPRD:01557(in vitro;in vivo)  ViewAnalyzing
6RAD51RAD51_HUMANY315RICKI Y DSPCL 8.89%ABL1 Phospho.ELM 7.0  ViewAnalyzing