|Description: Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).|
Ensembl ID: ENSG00000184990
UniprotKB/SwissProt: SIVA_HUMAN (O15304)
Function: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa- B and promotes T-cell receptor-mediated apoptosis.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Note=In the nucleus, accumulates in dot-like structures.