Regulatory Network in Protein Phosphorylation
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Substrate: SIVA1

Description: Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).

Synonyms: SIVA

Ensembl ID: ENSG00000184990

UniprotKB/SwissProt: SIVA_HUMAN (O15304)

Function: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa- B and promotes T-cell receptor-mediated apoptosis.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=In the nucleus, accumulates in dot-like structures.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of SIVA1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1SIVA1SIVA_HUMANY34VCAER Y SQEVF 13.25%ABL2 Swiss-Prot 55.0   ViewAnalyzing
2SIVA1SIVA_HUMANY34VCAER Y SQEVF 13.25%ABL2 Phospho.ELM 7.0  ViewAnalyzing