Regulatory Network in Protein Phosphorylation
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Substrate: TP73

Description: Tumor protein p73 (p53-like transcription factor) (p53-relatedprotein).

Synonyms: P73

Ensembl ID: ENSG00000078900

UniprotKB/SwissProt: P73_HUMAN (O15350)

Function: Participates in the apoptotic response to DNA damage. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of TP73

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1TP73P73_HUMANS47VGGTD S SMDVF 27.66%CHK1 Phospho.ELM 7.0  ViewAnalyzing
2TP73P73_HUMANT86SASPY T PEHAA 26.11%CDK2 HPRD:03587(in vitro;in vivo)  ViewAnalyzing
3TP73P73_HUMANT86SASPY T PEHAA 26.11%CDK2 Phospho.ELM 7.0  ViewAnalyzing
4TP73P73_HUMANT86SASPY T PEHAA 26.11%CDC2 HPRD:03587(in vitro;in vivo)  ViewAnalyzing
5TP73P73_HUMANY99PTHSP Y AQPSS 22.38%ABL1 Swiss-Prot 55.0   ViewAnalyzing
6TP73P73_HUMANY99PTHSP Y AQPSS 22.38%ABL1 HPRD:03587(in vitro;in vivo)  ViewAnalyzing
7TP73P73_HUMANY99PTHSP Y AQPSS 22.38%ABL1 Phospho.ELM 7.0  ViewAnalyzing