Regulatory Network in Protein Phosphorylation
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Substrate: WASF2

Description: Wiskott-Aldrich syndrome protein family member 2 (WASP family proteinmember 2) (Protein WAVE-2) (Verprolin homology domain-containingprotein 2).

Synonyms: WAVE2

Ensembl ID: ENSG00000158195

UniprotKB/SwissProt: WASF2_HUMAN (Q9Y6W5)

Function: Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton (By similarity). Cell projection, lamellipodium (By similarity). Note=At the interface between the lamellipodial actin meshwork and the membrane (By similarity).
PDB:2A40
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of WASF2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1WASF2WASF2_HUMANY150EALKF Y TDPSY 14.51%ABL1 Phospho.ELM 7.0  ViewAnalyzing
2WASF2WASF2_HUMANS482IAVEY S DSEDD 22.58% Swiss-Prot 55.0 View   
3WASF2WASF2_HUMANS484VEYSD S EDDSS 36.66% Swiss-Prot 55.0 View   
4WASF2WASF2_HUMANS488DSEDD S SEFDE 44.05% Swiss-Prot 55.0 View   
5WASF2WASF2_HUMANS489SEDDS S EFDED 49.64% Swiss-Prot 55.0 View