Regulatory Network in Protein Phosphorylation
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Substrate: PKIA

Description: cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) (cAMP-dependent protein kinase inhibitor, muscle/brain isoform).

Synonyms: PRKACN1

Ensembl ID: ENSG00000171033

UniprotKB/SwissProt: IPKA_HUMAN (P61925)

Function: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
PDB:1CMK
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PKIA

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PKIAIPKA_HUMANY8DVETT Y ADFIA 16.16%EGFR HPRD:05828(in vitro)  ViewAnalyzing
2PKIAIPKA_HUMANY8DVETT Y ADFIA 16.16%EGFR Phospho.ELM 7.0  ViewAnalyzing