Regulatory Network in Protein Phosphorylation
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Substrate: PLD2

Description: Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2)(Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).

Ensembl ID: ENSG00000129219

UniprotKB/SwissProt: PLD2_HUMAN (O14939)

Function: May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Peripheral membrane protein (By similarity).
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PLD2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PLD2PLD2_HUMANT72AQVVG T ERYTS 12.99% Phospho.ELM 7.0View   
2PLD2PLD2_HUMANT99GDFSW T TKKKY 27.78% Phospho.ELM 7.0View   
3PLD2PLD2_HUMANT100DFSWT T KKKYR 34.31% Phospho.ELM 7.0View   
4PLD2PLD2_HUMANS134FAVAY S PARDA 11.44% Phospho.ELM 7.0View   
5PLD2PLD2_HUMANS146NREMP S LPRAG 50.09% Phospho.ELM 7.0View   
6PLD2PLD2_HUMANY179LTMSF Y RNYHA 7.22%EGFR HPRD:03857(in vivo)  ViewAnalyzing
7PLD2PLD2_HUMANS243LVVKD S FLLYM 16.45%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
8PLD2PLD2_HUMANT252YMCLE T GAISF 20.97%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing