Regulatory Network in Protein Phosphorylation
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Substrate: RASA1

Description: Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Rasp21 protein activator) (p120GAP) (RasGAP).

Synonyms: RASA

Ensembl ID: ENSG00000145715

UniprotKB/SwissProt: RASA1_HUMAN (P20936)

Function: Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.
PDB:1WER
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of RASA1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1RASA1RASA1_HUMANY460DGKEI Y NTIRR 13.82%LCK HPRD:00745(in vitro;in vivo)  ViewAnalyzing
2RASA1RASA1_HUMANY460DGKEI Y NTIRR 13.82%EGFR HPRD:00745(in vitro;in vivo)  ViewAnalyzing
3RASA1RASA1_HUMANY460DGKEI Y NTIRR 13.82%EGFR Phospho.ELM 7.0  ViewAnalyzing
4RASA1RASA1_HUMANY460DGKEI Y NTIRR 13.82%PDGFR_group Phospho.ELM 7.0 ViewAnalyzing
5RASA1RASA1_HUMANY615HFTNP Y CNIYL 10.53% Swiss-Prot 55.0 View   
6RASA1RASA1_HUMANY615HFTNP Y CNIYL 10.53% Phospho.ELM 7.0View