Regulatory Network in Protein Phosphorylation
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Substrate: VAV2

Description: Protein vav-2.

Ensembl ID: ENSG00000160293

UniprotKB/SwissProt: VAV2_HUMAN (P52735)

Function: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
PDB:2DLZ
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of VAV2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1VAV2VAV2_HUMANY142NDDDV Y RSLEE 11.07%EGFR Swiss-Prot 55.0   ViewAnalyzing
2VAV2VAV2_HUMANY142NDDDV Y RSLEE 11.07%EGFR HPRD:02694(in vivo)  ViewAnalyzing
3VAV2VAV2_HUMANY142NDDDV Y RSLEE 11.07%Lck Phospho.ELM 7.0  ViewAnalyzing
4VAV2VAV2_HUMANY142NDDDV Y RSLEE 11.07%EGFR Phospho.ELM 7.0  ViewAnalyzing
5VAV2VAV2_HUMANY159LGEDI Y DCVPC 18.66%EGFR Swiss-Prot 55.0   ViewAnalyzing
6VAV2VAV2_HUMANY159LGEDI Y DCVPC 18.66%Lck Phospho.ELM 7.0  ViewAnalyzing
7VAV2VAV2_HUMANY159LGEDI Y DCVPC 18.66%EGFR Phospho.ELM 7.0  ViewAnalyzing
8VAV2VAV2_HUMANY159LGEDI Y DCVPC 18.66%EGFR HPRD:02694(in vitro;in vivo)  ViewAnalyzing
9VAV2VAV2_HUMANY172GGDDI Y EDIIK 17.97%EGFR HPRD:02694(in vivo)  ViewAnalyzing
10VAV2VAV2_HUMANY172GGDDI Y EDIIK 17.97%Lck Phospho.ELM 7.0  ViewAnalyzing
11VAV2VAV2_HUMANY172GGDDI Y EDIIK 17.97%EGFR Swiss-Prot 55.0   ViewAnalyzing
12VAV2VAV2_HUMANY172GGDDI Y EDIIK 17.97%EGFR Phospho.ELM 7.0  ViewAnalyzing