|Description: Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1pprotein).|
Ensembl ID: ENSG00000085832
UniprotKB/SwissProt: EP15_HUMAN (P42566)
Function: Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Recruited to the plasma membrane upon EGFR activation and localizes to coated pits (By similarity).