Regulatory Network in Protein Phosphorylation
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Substrate: EFNB2

Description: Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5)(LERK-5) (HTK ligand) (HTK-L).

Synonyms: EPLG5, HTKL, LERK5

Ensembl ID: ENSG00000125266

UniprotKB/SwissProt: EFNB2_HUMAN (P52799)

Function: Binds to the receptor tyrosine kinases EPHB4 and EPHA3. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of EFNB2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1EFNB2EFNB2_HUMANY304VFCPH Y EKVSG 11.55% Swiss-Prot 55.0 View   
2EFNB2EFNB2_HUMANY304VFCPH Y EKVSG 11.55% HPRD:02754(in vivo)View   
3EFNB2EFNB2_HUMANY304VFCPH Y EKVSG 11.55%EphB2 Phospho.ELM 7.0  ViewAnalyzing
4EFNB2EFNB2_HUMANY311KVSGD Y GHPVY 22.36% Phospho.ELM 7.0View   
5EFNB2EFNB2_HUMANY316YGHPV Y IVQEM 10.38% Phospho.ELM 7.0View   
6EFNB2EFNB2_HUMANY330SPANI Y YKV 9.31% Swiss-Prot 55.0 View   
7EFNB2EFNB2_HUMANY330SPANI Y YKV 9.31% Phospho.ELM 7.0View   
8EFNB2EFNB2_HUMANY330SPANI Y YKV 9.31% HPRD:02754(in vivo)View