Regulatory Network in Protein Phosphorylation
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Substrate: EPHA8

Description: Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-proteinkinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

Synonyms: EEK, KIAA1459

Ensembl ID: ENSG00000070886

UniprotKB/SwissProt: EPHA8_HUMAN (P29322)

Function: Receptor for members of the ephrin-A family.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.
PDB:1UCV
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of EPHA8

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1EPHA8EPHA8_HUMANY616AEPHT Y EEPGR 18.43%autocatalysis  Swiss-Prot 55.0 (Similarity) ViewAnalyzing
2EPHA8EPHA8_HUMANY616AEPHT Y EEPGR 18.43%EphA8 HPRD:01493(in vitro)  ViewAnalyzing
3EPHA8EPHA8_HUMANY616AEPHT Y EEPGR 18.43%EphA8 Phospho.ELM 7.0  ViewAnalyzing
4EPHA8EPHA8_HUMANY839YGERP Y WNMTN 18.68%autocatalysis  Swiss-Prot 55.0 (Similarity) ViewAnalyzing
5EPHA8EPHA8_HUMANY839YGERP Y WNMTN 18.68%EphA8 HPRD:01493(in vitro)  ViewAnalyzing
6EPHA8EPHA8_HUMANY839YGERP Y WNMTN 18.68%EphA8 Phospho.ELM 7.0  ViewAnalyzing