Regulatory Network in Protein Phosphorylation
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Substrate: EPHB1

Description: Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-proteinkinase receptor EPH-2) (NET) (HEK6) (ELK).

Synonyms: EPHT2, NET

Ensembl ID: ENSG00000154928

UniprotKB/SwissProt: EPHB1_HUMAN (P54762)

Function: Receptor for members of the ephrin-B family. Binds to ephrin-B1, -B2 and -B3. May be involved in cell-cell interactions in the nervous system.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.
PDB:2EAO
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of EPHB1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1EPHB1EPHB1_HUMANY594PGMKI Y IDPFT 8.18% Phospho.ELM 7.0View   
2EPHB1EPHB1_HUMANY594PGMKI Y IDPFT 8.18%autocatalysis Swiss-Prot 55.0  ViewAnalyzing
3EPHB1EPHB1_HUMANY594PGMKI Y IDPFT 8.18%EphB1 HPRD:02790(in vitro;in vivo)  ViewAnalyzing
4EPHB1EPHB1_HUMANY600IDPFT Y EDPNE 20.79%autocatalysis  Swiss-Prot 55.0 (Potential) ViewAnalyzing
5EPHB1EPHB1_HUMANY600IDPFT Y EDPNE 20.79% HPRD:02790(in vivo)View   
6EPHB1EPHB1_HUMANY600IDPFT Y EDPNE 20.79% Phospho.ELM 7.0View   
7EPHB1EPHB1_HUMANY778TSDPT Y TSSLG 15.26%autocatalysis  Swiss-Prot 55.0 (Potential) ViewAnalyzing
8EPHB1EPHB1_HUMANY778TSDPT Y TSSLG 15.26% Phospho.ELM 7.0View   
9EPHB1EPHB1_HUMANY928IKMVQ Y RDSFL 12.65%EphB1 HPRD:02790(in vivo)  ViewAnalyzing
10EPHB1EPHB1_HUMANY928IKMVQ Y RDSFL 12.65%autocatalysis Swiss-Prot 55.0  ViewAnalyzing
11EPHB1EPHB1_HUMANS968KKILN S IHSMR 20.45% Swiss-Prot 55.0 View