Regulatory Network in Protein Phosphorylation
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Substrate: EPHB3

Description: Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-proteinkinase receptor HEK-2) (Tyrosine-protein kinase TYRO6).

Synonyms: ETK2, HEK2, TYRO6

Ensembl ID: ENSG00000182580

UniprotKB/SwissProt: EPHB3_HUMAN (P54753)

Function: Receptor for members of the ephrin-B family. Binds to ephrin-B1 and -B2.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of EPHB3

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1EPHB3EPHB3_HUMANY608PGMKV Y IDPFT 8.29%autocatalysis  Swiss-Prot 55.0 (Similarity) ViewAnalyzing
2EPHB3EPHB3_HUMANY608PGMKV Y IDPFT 8.29% Phospho.ELM 7.0View   
3EPHB3EPHB3_HUMANY608PGMKV Y IDPFT 8.29% HPRD:03502(in vivo)View   
4EPHB3EPHB3_HUMANY614IDPFT Y EDPNE 20.79%autocatalysis  Swiss-Prot 55.0 (Similarity) ViewAnalyzing
5EPHB3EPHB3_HUMANY614IDPFT Y EDPNE 20.79%EphB3 HPRD:03502(in vitro;in vivo)  ViewAnalyzing
6EPHB3EPHB3_HUMANY614IDPFT Y EDPNE 20.79%EphB3 Phospho.ELM 7.0  ViewAnalyzing
7EPHB3EPHB3_HUMANY792PSDPT Y TSSLG 15.26%autocatalysis  Swiss-Prot 55.0 (Potential) ViewAnalyzing
8EPHB3EPHB3_HUMANY942IKMGR Y KESFV 17.24%autocatalysis  Swiss-Prot 55.0 (Similarity) ViewAnalyzing