|Description: Serine/threonine-protein kinase 6 (EC 18.104.22.168) (Aurora kinase A)(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)(Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase).|
Synonyms: AIK, ARK1, AURA, BTAK, STK15, STK6
Ensembl ID: ENSG00000087586
UniprotKB/SwissProt: STK6_HUMAN (O14965)
Function: May play a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Maybe involved in microtubule formation and/or stabilization. May play a key role during tumor development and progression.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Centrosome. Spindle. Note=Localizes on centrosomes in interphase cells and at each spindle pole in mitosis.