|Description: Histone H3.1 (H3/a) (H3/b) (H3/c) (H3/d) (H3/f) (H3/h) (H3/i) (H3/j)(H3/k) (H3/l).|
Ensembl ID: ENSG00000112727
UniprotKB/SwissProt: H31_HUMAN (P68431)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.