Regulatory Network in Protein Phosphorylation
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Substrate: KIF2C

Description: Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin)(MCAK) (Kinesin-like protein 6).

Synonyms: KNSL6

Ensembl ID: ENSG00000142945

UniprotKB/SwissProt: KIF2C_HUMAN (Q99661)

Function: Present throughout the cell cycle, associates with centromeres at early prophase, and remains associated with the centromere until after telophase (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton (By similarity). Nucleus (By similarity). Centromere (By similarity).
PDB:2HEH
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of KIF2C

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1KIF2CKIF2C_HUMANS95KQKRR S VNSKI 29.68%AurB(Aurora B) Phospho.ELM 7.0 ViewAnalyzing
2KIF2CKIF2C_HUMANS628EEEEL S SQMSS 23.08% Swiss-Prot 55.0 View   
3KIF2CKIF2C_HUMANS629EEELS S QMSSF 42.39% Swiss-Prot 55.0 View   
4KIF2CKIF2C_HUMANS632LSSQM S SFNEA 24.92% Swiss-Prot 55.0 View   
5KIF2CKIF2C_HUMANS633SSQMS S FNEAM 27.09% Swiss-Prot 55.0 View