|Description: Cofilin-2 (Cofilin, muscle isoform).|
Ensembl ID: ENSG00000165410
UniprotKB/SwissProt: COF2_HUMAN (Q9Y281)
Function: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus matrix (By similarity). Cytoplasm, cytoskeleton (By similarity).