Regulatory Network in Protein Phosphorylation
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Substrate: MAP3K9

Description: Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixedlineage kinase 1).

Synonyms: MLK1, PRKE1

Ensembl ID: ENSG00000006432

UniprotKB/SwissProt: M3K9_HUMAN (P80192)

Function: Activates the JUN N-terminal pathway.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of MAP3K9

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1MAP3K9M3K9_HUMANT304REWHR T TKMSA 20.20%autocatalysis Swiss-Prot 55.0  ViewAnalyzing
2MAP3K9M3K9_HUMANS308RTTKM S AAGTY 19.27%autocatalysis Swiss-Prot 55.0  ViewAnalyzing
3MAP3K9M3K9_HUMANT312MSAAG T YAWMA 12.82%autocatalysis Swiss-Prot 55.0  ViewAnalyzing
4MAP3K9M3K9_HUMANT312MSAAG T YAWMA 12.82% Phospho.ELM 7.0View   
5MAP3K9M3K9_HUMANT312MSAAG T YAWMA 12.82%MLK1 HPRD:15965(in vitro)  ViewAnalyzing
6MAP3K9M3K9_HUMANS552SSPPA S PTIIP 28.49% Swiss-Prot 55.0 (Similarity)View   
7MAP3K9M3K9_HUMANS931LLASR S PSSNG 27.00% Swiss-Prot 55.0 (Similarity)View   
8MAP3K9M3K9_HUMANS934SRSPS S NGLSP 38.00% Swiss-Prot 55.0 (Similarity)View   
9MAP3K9M3K9_HUMANS998PRPRP S ANRQR 39.18% Swiss-Prot 55.0 (Similarity)View