|Description: Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers againstDPP homolog 1) (Mad-related protein 1) (Transforming growth factor-beta-signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).|
Synonyms: BSP1, MADH1, MADR1
Ensembl ID: ENSG00000170365
UniprotKB/SwissProt: SMAD1_HUMAN (Q15797)
Function: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.