|Description: STAM-binding protein (EC 22.214.171.124) (Associated molecule with the SH3domain of STAM).|
Ensembl ID: ENSG00000124356
UniprotKB/SwissProt: STABP_HUMAN (O95630)
Function: May function as a ubiquitin-protein or polyubiquitin hydrolase. This deubiquitinating enzyme which functions at the endosome, is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Membrane; Peripheral membrane protein. Cytoplasm.